298. And while establishing their own relationships and responses to life, the readers often find that the characters in their stories are going though similar adjustments, which help to clarify and give significance to their own.
本句的主干是readers often find that…，其中，while引导的是时间状语从句；find的宾语是由that引导的宾语从句，即that the characters...similar adjustments;非限制性定语从句which help...to their own用来修饰前面所述的事件。
give significance to意为“赋予……重要性，赋予……重大意义”。如:
The great ideal would give significance to a life of human being.崇高的理想能够赋予人们的生命以重大意义。